Immunology

Interleukin-11 found to ameliorate acute colitis in mice

Interleukin (IL)-11 is produced by inflammatory fibroblasts, one of the stromal cells, during acute colitis. Researchers at Toho University Japan found that IL-11 ameliorated acute colitis in mouse models. The IL-11 production ...

Medications

Scientists test new way to treat eczema

Researchers at Vanderbilt University Medical Center have developed a new investigational drug that can block inflammatory signaling in a preclinical model of atopic dermatitis—eczema.

Inflammatory disorders

From grave to cradle: Collagen-induced gut cell reprogramming

Most cells have a pretty normal life: they're born, they grow, they get old, and they die. But the Benjamin Buttons of the cellular world can go from old to young again in the right context. Now, researchers from Japan have ...

Psychology & Psychiatry

Stem cells may help identify new schizophrenia drugs

Inflammation and overactivation of the immune system in the brain can cause loss of synapses and the death of neurons, leading to neurodegenerative and psychiatric diseases.

Diseases, Conditions, Syndromes

Scientists find key reason why loss of smell occurs in long COVID-19

The reason some people fail to recover their sense of smell after COVID-19 is linked to an ongoing immune assault on olfactory nerve cells and an associated decline in the number of those cells, a team of scientists led by ...

Medical research

RXR, the cell protein that keeps blood stem cells young and fit

The cell protein retinoid X receptor (RXR) is a key factor in the maintenance of hematopoietic stem cells, the immature stem cells that give rise to all the blood cell lineages. RXR ensures that these cells remain youthful ...

Medical research

Blood clotting research holds hope for sepsis

Researchers from the University of Birmingham, UK, who identified a novel mechanism for platelet activation in pathogenic blood clotting (thrombosis) are now turning their attention to sepsis.

Immunology

Researchers find missing piece of the asthma puzzle

An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma. According to the new research from scientists at La Jolla Institute for Immunology (LJI), therapeutics ...

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