Inflammatory disorders

Environmental chemicals increase risk of inflammatory bowel disease

Inflammatory bowel disease (IBD), a condition characterized by chronic gastrointestinal inflammation, is becoming increasingly common in industrialized countries. While researchers have identified approximately 200 genetic ...

Medical research

Innate immunity: The final touch for antimicrobial defense

If bacteria enter the body, it often takes just a few minutes for the innate immune system to recognize them as foreign and set the immune defense in motion. Receptors of the immune system that recognize bacterial cell wall ...

Arthritis & Rheumatism

How mitochondrial damage ignites the 'auto-inflammatory fire'

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and ...

Diseases, Conditions, Syndromes

Immune system culprit in severe COVID cases found

Yale researchers have identified a particular immune response pathway that leads to severe illness and death in people infected by the SARS-CoV-2 virus.

Diseases, Conditions, Syndromes

Scientists find a new anti-hepatic fibrosis drug target

Scientists from Russia and Italy studied a new axis of the pathway that prevents the development of liver fibrosis. The role of GILZ protein in curbing the disease progression was shown in a study using mice models and confirmed ...

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