Effector regulatory T cells (eTreg cells) are a specialized subset of white blood cells that keep the immune system in check. St. Jude Children's Research Hospital scientists have revealed the metabolic signaling mechanisms ...
Nov 17, 2020
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49
The popular painkiller ibuprofen may have more significant effects on the liver than previously thought, according to new research from the University of California, Davis. The study in laboratory mice also shows marked differences ...
Mar 11, 2020
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644
Once a vague scapegoat for a variety of ills, increasing evidence suggests a condition known as "leaky gut"—in which microbes and other molecules seep out of the intestines—may be more common, and more harmful, than previously ...
Feb 10, 2020
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426
In a study by The Wistar Institute and collaborators, a rare, African-specific variant of the TP53 gene called P47S causes iron accumulation in macrophages and other cell types and is associated with poorer response to bacterial ...
Jan 24, 2020
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135
Pharmaceutical companies once considered a protein called p38 a very attractive target for treating rheumatoid arthritis. Arthritis patients usually have elevated activity of this inflammation-producing protein, and in lab ...
Mar 7, 2018
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134
National Institutes of Health researchers have discovered a rare and sometimes lethal inflammatory disease - otulipenia - that primarily affects young children. They have also identified anti-inflammatory treatments that ...
Aug 22, 2016
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433
A molecular pathway that is activated in the brain during fasting helps halt the spread of intestinal bacteria into the bloodstream, according to a new study by a team of researchers at the Salk Institute.
May 17, 2016
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2543
Researchers from the University of Leicester and University Hospitals of Leicester NHS Trust, working with the National Institute of Allergy and Infectious Diseases (NIAID) and Genentech, have discovered new insights into ...
Aug 19, 2015
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113
The survival and proliferation of usually harmless Escherichia coli in the gut of inflammatory bowel disease patients may now be better understood, as researchers have defined a fundamental mechanism through which the bacteria ...
May 12, 2015
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88
Almost all injuries, even minor skin scratches, trigger an inflammatory response, which provides protection against invading microbes but also turns on regenerative signals needed for healing and injury repair - a process ...
Feb 25, 2015
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