When the bacterium Helicobacter pylori infects the stomach, it causes gastric inflammation and increases the risk of stomach cancer. A team of researchers from Charité—Universitätsmedizin Berlin and the Max Delbrück ...
Apr 20, 2022
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131
An important task of the human immune system is to maintain the critical balance between efficient defense against a pathogen on the one hand and protection of affected tissues on the other. Disease patterns of viral infections ...
Feb 16, 2022
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10
Mutations in the enzyme IDH (isocitrate dehydrogenase) are found in 15–20% of acute myeloid leukemia (AML) cases. IDH mutations have been shown to impact cellular differentiation and DNA and histone methylation, but little ...
Dec 13, 2021
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An exciting new way has been found in which the body senses a bacterial infection within 4 hours and uses nerve pathways to trigger an immune response in distant organs. The speed by which an infection can be identified, ...
May 21, 2021
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7
Scientists from Russia and Italy studied a new axis of the pathway that prevents the development of liver fibrosis. The role of GILZ protein in curbing the disease progression was shown in a study using mice models and confirmed ...
May 4, 2021
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10
Dec. 30, 2020—When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with ...
Dec 31, 2020
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Once a vague scapegoat for a variety of ills, increasing evidence suggests a condition known as "leaky gut"—in which microbes and other molecules seep out of the intestines—may be more common, and more harmful, than previously ...
Feb 10, 2020
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426
Researchers at the University of Illinois at Chicago have identified a molecular switch that causes immune cells called macrophages to clean up cellular debris caused by infections instead of contributing to inflammation ...
Jul 31, 2019
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850
The protein BRAF is a key player in the development of many different types of cancer, including melanoma. Scientists have known that BRAF becomes activated by growth factors and subsequently stimulates downstream proteins ...
Apr 24, 2019
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8
In old age, the amount of stem cells in the brains of mice decreases drastically. The remaining ones protect themselves from completely vanishing by entering a state of dormancy, scientists from the German Cancer Research ...
Feb 28, 2019
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