Fatty acid metabolism is an essential process in tumor growth and proliferation. Despite attempts to block fatty acid metabolism as a therapeutic strategy to reduce tumor size and growth, the outcome has not always been positive. ...
Feb 6, 2019
0
79
Korean researchers have identified the inhibition of autophagy in microglia, brain immune cells. It is expected to help develop treatments for Alzheimer's disease which occur due to the inhibition of autophagy.
Jan 18, 2019
0
5
High-grade serous carcinoma is the most aggressive form of ovarian cancer and accounts for the majority of advanced-stage cases. The poor outcomes associated with the disease underscore the need for more effective treatments. ...
Mar 16, 2022
0
61
When you park in the office car park, you usually have no problem finding your car again at the end of the day. The next day, you might park a few spots further away. However, in the evening, you find your car, even though ...
Nov 5, 2018
0
33
Like snakes, tumour cells shed their skin. Cancer is not a static disease but during its development the disease accumulates changes to evade natural defences adapting to new environmental circumstances, protecting against ...
Sep 2, 2011
0
0
Combined treatment with two drugs targeting different points in the same growth-factor pathway delayed the development of treatment resistance in patients with BRAF-positive metastatic malignant melanoma. The results of a ...
Sep 29, 2012
0
0
PCSK9 inhibition is a new therapeutic strategy for atherosclerosis which is known to lower LDL cholesterol. Research from Karolinska Institutet, presented at the ESC Congress last year and now published in the Journal of ...
Apr 6, 2018
0
4
Cancer cells with mutations in BRCA1 or BRCA2 genes, which serve a vital role in preserving the integrity of the genetic code, are key targets for cancer therapeutics. Yet, few agents can selectively eliminate cells deficient ...
Nov 5, 2015
1
123
(Medical Xpress) -- Scientists at the Friedrich Miescher Institute for Biomedical Research have discovered a potential new approach for inhibiting the growth of pathogenic fungi. Their findings on the mechanism in question ...
Aug 30, 2011
0
0
Brensocatib did not improve the clinical status of patients hospitalized with severe SARS-CoV-2 infection in the double-blind randomized, placebo-controlled STOP-COVID19 multicenter clinical trial, according to research published ...
May 18, 2022
0
5
