Neuroscience

Uncovering the role of somatostatin signaling in the brain

Somatostatin, a signaling molecule produced by many inhibitory neurons in the brain, broadly dampens communication among a variety of cell types in the prefrontal cortex and promotes exploratory and risk-taking-like behavior ...

Neuroscience

Somatostatin neurons cooperate in the cerebral cortex

The brain's cerebral cortex is made up of distinct regions involved in myriad processes, from sensory perception to cognitive functions like memory, attention, and decision-making. University of Pittsburgh neuroscience researchers ...

Neuroscience

How different flavors of inhibition save the day

During development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibitory neuron subtypes are known to influence circuit dynamics, but how they interact with plasticity ...

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