Neuroscience

What happens when synapses run out of transmitter?

(Medical Xpress)—The recent Nobel Prize Award in Medicine highlights the importance of vesicle-based transport for different kinds of cells. One of the recipients, Thomas Sudhof, has contributed extensively to our current ...

Neuroscience

Researchers cure epilepsy in mice using brain cells

UCSF scientists controlled seizures in epileptic mice with a one-time transplantation of medial ganglionic eminence (MGE) cells, which inhibit signaling in overactive nerve circuits, into the hippocampus, a brain region associated ...

Neuroscience

Perfect balance: How the brain fine-tunes its sensitivity

A sensitive perception of the environment is crucial for guiding our behavior. However, an overly sensitive response of the brain's neural circuits to stimuli can lead to neurodevelopmental disorders such as epilepsy. University ...

Neuroscience

Uncovering the role of somatostatin signaling in the brain

Somatostatin, a signaling molecule produced by many inhibitory neurons in the brain, broadly dampens communication among a variety of cell types in the prefrontal cortex and promotes exploratory and risk-taking-like behavior ...

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