By sequencing cancer-cell genomes, scientists have discovered vast numbers of genes that are mutated, deleted or copied in cancer cells. This treasure trove is a boon for researchers seeking new drug targets, but it is nearly ...
Aug 15, 2012
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Alzheimer's disease, which is expected to have affected about 6.7 million patients in the U.S. in 2023, results in a substantial loss of brain cells. But the events that cause neuron death are poorly understood.
Jan 18, 2024
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Insights that pave the way for novel therapeutic approaches to tackle cancer, fibrosis, and many age-related conditions have been uncovered by a team of scientists, including researchers from UCL.
Nov 29, 2023
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Immediately after the infection of a cell in the throat or lungs, the SARS-CoV-2 virus works very hard to replicate, using the human cell's metabolic pathways to produce its proteins and make sure that its genetic material ...
Aug 21, 2023
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In November 2018, the Camp Fire burned a total of 239 square miles, destroyed 18,804 structures and killed 85 people, making it the deadliest and most destructive wildfire in California history.
Jan 18, 2023
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Researchers from the Laboratory of Oncolytic-Virus-Immuno-Therapeutics (LOVIT) at the LIH Department of Oncology (DONC) are working on the development of novel anticancer strategies based on oncolytic viruses, 'good' viruses ...
Jun 29, 2021
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The chemotherapy drug decitabine is commonly used to treat patients with blood cancers, but its response rate is somewhat low. Researchers have now identified why this is the case, opening the door to more personalized cancer ...
May 24, 2021
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A research group at the RIKEN Center for Biosystems Dynamics Research (BDR) has discovered molecular events that determine whether cancer cells live or die. With this knowledge, they found that reduced consumption of a specific ...
Apr 27, 2021
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A team of researchers affiliated with a host of institutions across Japan has found that inhibiting kidney-type glutaminase-dependent glutaminolysis in mice can lead to elimination of senescent cells. In their paper published ...
Neurodevelopmental disorders, including schizophrenia and autism, likely result from complex interactions that modify the effects of individual genes. In a new study, researchers evaluated the effects of over 300 pairwise ...
Feb 14, 2020
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