Health

Host-microbe interactions in the gut

Although the mutually beneficial relationship between human beings and gut microbes is clear, how we—the host—affect the functions of gut microbial communities remains poorly understood.

Immunology

Immune cells drive gallstone formation

Sticky meshworks of DNA and proteins extruded by white blood cells called neutrophils act as the glue that binds together calcium and cholesterol crystals during gallstone formation, researchers in Germany report August 15 ...

Immunology

Intestinal immune cell interactions

Multiple types of immune cells are interspersed among the epithelial cells lining the intestines and are considered to be a first line of defense against pathogens. The survival and interaction of these intraepithelial lymphocytes ...

Immunology

Innate immune responses to high-fat diets lead to obesity

Why is eating a high fat diet a recipe for obesity? According to a new study from the RIKEN Center for Integrative Medical Sciences (IMS) in Japan, the answer involves the activity of a specific type of immune cell that lives ...

Medical research

A new strategy 'raises the volume' of gut-body communication

Throughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells and, although they comprise only a small population of the total cells, they are one of the most important moderators ...

Medical research

Tissue engineering: The big picture on growing small intestines

Babies born prematurely often face intense medical challenges, including intestines that are underdeveloped or diseased. While an intestine transplant can benefit some patients, many babies are simply too small to endure ...

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