Diseases, Conditions, Syndromes

Tumor necrosis factor in colitis—bad actor or hero?

Investigators at Children's Hospital Los Angeles have found that a common therapeutic target for the treatment of inflammatory bowel disease (IBD) may actually protect against intestinal inflammation by inhibiting pathogenic ...

Inflammatory disorders

Small intestine contributes to chronic inflammation in obesity

Obesity is caused by numerous and complex factors, some of which are as yet unsuspected. Scientists from the CNRS, INSERM, UPMC and Université Paris Descartes, working with research clinicians from Paris Public Hospitals ...

Oncology & Cancer

'Genomic catastrophe' may cause normal cells to become cancerous

Although there is no one established universal cause of cancer, genetic changes are central to its development. The accumulation of spontaneous genetic changes, or mutations, that occur when cells divide can be hastened by ...

Medical research

Cancer-linked protein helps control fate of intestinal stem cells

An international group of researchers has shown that a regulatory protein involved in controlling how cancer spreads through the body also influences the fate of stem cells in the intestine of mice. The results, which are ...

Diseases, Conditions, Syndromes

New insight into inflammatory bowel disease

The development of inflammatory bowel disease (IBD) may be influenced through a protein in the gut leading to inflammation according to research.

Medical research

Growing human GI cells may lead to personalized treatments

(Medical Xpress)—A method of growing human cells from tissue removed from a patient's gastrointestinal (GI) tract eventually may help scientists develop tailor-made therapies for inflammatory bowel disease and other GI ...

Immunology

'Normal' bacteria vital for keeping intestinal lining intact

Scientists at Albert Einstein College of Medicine of Yeshiva University have found that bacteria that aid in digestion help keep the intestinal lining intact. The findings, reported online in the journal Immunity, could yield ...

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