Medical research

Mitochondria control stem cell fate

What happens in intestinal epithelial cells during a chronic illness? Basic research conducted at the Chair of Nutrition and Immunology at the Technical University of Munich (TUM) addressed this question by generating a new ...

Medical research

Gut model HuMiX works like the real thing

One of the most complex human organs is the digestive tract: Here, the body comes into contact with all manner of diet-derived compounds and with countless bacteria. Scientists from the Luxembourg Centre for Systems Biomedicine ...

Medical research

Controlling cell turnover in the intestinal lining

The lining of the intestine is the most rapidly-renewing tissue in the body. Routine shedding of epithelial cells from this lining is a key element of tissue turnover, and is thus essential to maintaining optimal health. ...

Medical research

A cultural revolution in the study of the gut microbiome

It's estimated that as many as 1,000,000 Americans suffer from inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, which cause mild to severe symptoms that at best can be managed and at worst ...

Medical research

Using intestinal organoids to study salmonella

One of the main causes of food poisoning is Salmonella enterica. This bacterium infects cells in the intestinal epithelium that lines our gut, leading to painful stomach cramps, diarrhoea and fever. One major difficulty in ...

Diseases, Conditions, Syndromes

Study identifies key protein that contributes to colitis

The cause of Ulcerative Colitis, a debilitating disease of the intestine, is unclear. A Yale-led study has illuminated the role of a protein that plays a key part in the development of the condition. The research, published ...

Medical research

Your gut development during infancy can have lifelong implications

The suckling period (infancy) in mice is critical for epigenetic changes (changes that affect the way genes are expressed) in the development of stem cells in the intestine, potentially affecting intestinal health for life. ...

page 9 from 12