Immunology

Human rotavirus manipulates immune response to maintain infection

The gut of a child infected with rotavirus is like a battle ground. On one side, the virus invades the epithelial cells that form the lining of the small intestine. The virus replicates driving havoc in the intestinal environment, ...

Oncology & Cancer

Common food additive promotes colon cancer in mice

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter intestinal bacteria in a manner that promotes intestinal inflammation and colorectal cancer, according to a new study.

Medical research

Mitochondria control stem cell fate

What happens in intestinal epithelial cells during a chronic illness? Basic research conducted at the Chair of Nutrition and Immunology at the Technical University of Munich (TUM) addressed this question by generating a new ...

Medical research

Gut model HuMiX works like the real thing

One of the most complex human organs is the digestive tract: Here, the body comes into contact with all manner of diet-derived compounds and with countless bacteria. Scientists from the Luxembourg Centre for Systems Biomedicine ...

Medical research

A cultural revolution in the study of the gut microbiome

It's estimated that as many as 1,000,000 Americans suffer from inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, which cause mild to severe symptoms that at best can be managed and at worst ...

Oncology & Cancer

'Genomic catastrophe' may cause normal cells to become cancerous

Although there is no one established universal cause of cancer, genetic changes are central to its development. The accumulation of spontaneous genetic changes, or mutations, that occur when cells divide can be hastened by ...

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