Inflammatory disorders

Link between intestinal inflammation and microbiome

Around 500 to 1,000 different types of bacteria, fungi and other microorganisms colonize our intestines. All of them together form the intestinal microbiome. As we now know, these microbes play an important role in maintaining ...

Immunology

Systemic lupus erythematosus linked to altered gut microbiome

Systemic lupus erythematosis (SLE) is an autoimmune disease in which the immune system targets tissues of the body, causing widespread inflammation and affecting multiple organs such as the kidney and the brain. The gut "microbiome"—all ...

Immunology

Immunodeficiency affects intestinal microbiome

In the largest study of intestinal bacterial composition (also called the intestinal microbiome) to date in persons with the immunodeficiency selective IgA deficiency, researchers at DTU Bioengineering have ascertained that ...

Gastroenterology

How probiotic bacteria benefit the intestine

Interaction between the gut microbiota and the immune system is important for host physiology and susceptibility to disease, but also for the efficacy of e.g., cancer immunotherapies. A multidisciplinary research team have ...

Gerontology & Geriatrics

Age and aging have critical effects on the gut microbiome

Researchers at Cedars-Sinai have found that aging produces significant changes in the microbiome of the human small intestine distinct from those caused by medications or illness burden. The findings have been published in ...

Oncology & Cancer

How high-fat diets allow cancer cells to go unnoticed

A high-fat diet increases the incidence of colorectal cancer. Cold Spring Harbor Laboratory Fellow Semir Beyaz and collaborators from Harvard Medical School and Massachusetts Institute of Technology have discovered that ...

Immunology

Researchers identify enzyme linked to colitis

An enzyme that usually stops bacterial growth in the large intestine stimulates inflammation in some people, resulting in ulcerative colitis—a chronic digestive disease that affects more than 750,000 Americans, according ...

Medical research

Mom and baby share 'good bacteria' through breast milk

A new study by researchers at the University of British Columbia and the University of Manitoba has found that bacteria are shared and possibly transferred from a mother's milk to her infant's gut, and that breastfeeding ...

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