The master regulators of gut stem cells, called intestinal myofibroblasts, have pumps that protect them, and thus the gut, from the toxic effects of a wide range of compounds, including the anticancer drug tamoxifen, according ...
Aug 24, 2018
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The University of Toronto's David McMillen and his research team are creating a new life form to ward off disease – a bespoke, gut-dwelling microbe engineered to release drugs when needed.
Jun 12, 2018
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Researchers at the University of Zurich have discovered the identity of the stem-cell niche of the colon. The niche comprises special cells that activate the stem cells of the adjacent intestinal epithelium and are responsible ...
Jun 6, 2018
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As people age, their intestinal stem cells begin to lose their ability to regenerate. These stem cells are the source for all new intestinal cells, so this decline can make it more difficult to recover from gastrointestinal ...
May 3, 2018
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A new mechanism for regulating stem cells in the intestine of fruit flies has been discovered by researchers at Stockholm University. In addition, it was discovered that a certain protein can slow the growth of tumours in ...
Apr 19, 2018
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Dramatic calorie restriction, diets reduced by 40 percent of a normal calorie total, have long been known to extend health span, the duration of disease-free aging, in animal studies, and even to extend life span in most ...
Feb 22, 2018
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A bone marrow transplant is often the only therapy available to save leukaemia patients, but the risk of complications is high. Despite the considerable time and effort of finding a suitable donor, nearly half of all patients ...
Feb 22, 2018
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Investigators have demonstrated how cells of a human intestinal lining created outside an individual's body mirror living tissue when placed inside microengineered Intestine-Chips, opening the door to personalized testing ...
Feb 16, 2018
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A team of researchers at the University of Pittsburgh has found a possible way to protect cells in the intestines when subjected to chemotherapy. In their paper published in Science Translational Medicine, the team describes ...
New UCLA research could help explain the link between a high-cholesterol diet and an elevated risk for colon cancer.
Jan 25, 2018
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