Babies born prematurely often face intense medical challenges, including intestines that are underdeveloped or diseased. While an intestine transplant can benefit some patients, many babies are simply too small to endure ...
Jun 7, 2019
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The survival and fitness of multicellular organisms is tightly associated with their capacity to renew their tissues. This is particularly important for tissues that are permanently exposed to and challenged by the external ...
Jun 4, 2019
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One of the most exciting advancements in stem cell research has been the development of organoid systems, which are organ-like three-dimensional structures that mimic their corresponding organ in vivo. In this important review ...
Jun 3, 2019
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A sensational new study conducted at the University of Copenhagen disproves traditional knowledge of stem cell development. The study reveals that the destiny of intestinal cells is not predetermined, but instead determined ...
May 16, 2019
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Cells that line the intestinal tract are replaced every few days, a high rate of turnover that relies on a healthy population of intestinal stem cells. MIT and University of Tokyo biologists have now found that aging takes ...
Mar 28, 2019
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Researchers at Universitätsmedizin Berlin have discovered a protective mechanism which is used by the body to protect intestinal stem cells from turning cancerous. The body's innate immune system was found to play a pivotal ...
Feb 1, 2019
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An Osaka University-led research team has developed a system for simply and efficiently producing human norovirus. By coaxing human induced pluripotent stem cells (iPSCs) to develop into a type of cell that usually lines ...
Dec 11, 2018
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From a molecular perspective, the gut is a noisy place, where all manner of human and microbial cells communicate with one another to maintain a robust and healthy cellular community. Key to this community are intestinal ...
Nov 2, 2018
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The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. The c-MYC transcription factor controls the activity of a large number of genes involved in cell division, and its ...
Sep 5, 2018
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The master regulators of gut stem cells, called intestinal myofibroblasts, have pumps that protect them, and thus the gut, from the toxic effects of a wide range of compounds, including the anticancer drug tamoxifen, according ...
Aug 24, 2018
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