People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side ...
Apr 7, 2021
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In many patients with Crohn's disease abdominal fat migrates to the wall of the inflamed small intestines. What prompts the fat tissue to "creep" through the abdomen and wrap around the intestines of many patients with this ...
Oct 1, 2020
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Pioneering scientists at the Francis Crick Institute, Great Ormond Street Hospital (GOSH) and UCL Great Ormond Street Institute of Child Health (ICH) have grown human intestinal grafts using stem cells from patient tissue ...
Sep 8, 2020
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Researchers from Boston Medical Center's Maxwell Finland Laboratory for Infectious Diseases have identified properties in placenta tissue that may play an important role in preventing the transmission of COVID-19 from a mother ...
Sep 2, 2020
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According to findings published this week in mBio, Nissle, a strain of Escherichia coli, is harmless to intestinal tissue and may protect the gut from enterohemorrhagic E. coli, a pathogen that produces Shiga toxin.
Jul 7, 2020
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Necrotizing enterocolitis (NEC), a rare inflammatory bowel disease, primarily affects premature infants and is a leading cause of death in the smallest and sickest of these patients. The exact cause remains unclear, and there ...
May 6, 2020
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MIT engineers have devised a way to speed up the development of new drugs by rapidly testing how well they are absorbed in the small intestine. This approach could also be used to find new ways to improve the absorption of ...
Apr 27, 2020
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Patients with Alzheimer's disease (AD) are often prescribed drugs for other conditions—including diabetes or high blood pressure—at the same doses as those without dementia. That practice might need to be reexamined in ...
Apr 15, 2020
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Short bowel syndrome is a debilitating condition with few treatment options, and these treatments have limited efficacy. The ability to grow artificial intestine is a coveted goal with the potential to profoundly improve ...
Sep 18, 2019
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Researchers at the University of Helsinki have discovered how regenerative capacity of intestinal epithelium declines when we age. Targeting of an enzyme that inhibits stem cell maintaining signaling rejuvenates the regenerative ...
Jul 10, 2019
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