Bone homeostasis requires precise balance between deposition of new bone by osteoblasts and resorption of old bone by osteoclasts. Bone diseases, including osteoporosis and rheumatoid arthritis, are the result of increased ...
Dec 9, 2013
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Patients with the autoimmune disease systemic lupus erythematosus (SLE) produce autoantibodies that target can cause damage to multiple organ systems. The host factors that are targeted by autoantibodies produced by SLE patients ...
Nov 25, 2013
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Non-small cell lung cancer (NSCLC) is one of the leading causes of cancer deaths worldwide. Current therapies that target cellular kinases have been effective for some patients: however, many individuals with NSCLS do not ...
Nov 8, 2013
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One of the most devastating side effects of diabetes is kidney failure, and one of the earliest signs of kidney damage is a disruption of the organ's filtering capacity. Diabetes patients who develop kidney failure must go ...
Nov 8, 2013
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Epidemiological methods used during the investigation of fatal injuries makes the results more accurate, and allows for greater legal certainty of conclusions. Michael Freeman will address this as he defends his thesis at ...
Nov 6, 2013
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Vitamin D deficiency has been associated with kidney disease including fibrosis. Some studies have even suggested that treatment with vitamin D or vitamin D analogs can reduce renal fibrosis; however, the pathways targeted ...
Oct 25, 2013
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Clinical trial design for new cancer therapies has historically been focused on the tissue of origin of a tumor, but a paper from researchers at Memorial Sloan-Kettering Cancer Center published on September 26 in Nature Genetics ...
Sep 27, 2013
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Recreational drug use has been with us forever, and so have the challenges that this use brings to medicine and society. But the nature of the modern drug scene has changed to such an extent that the health systems of the ...
Sep 3, 2013
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Swiss researchers have developed a method that is able to reliably localise certain tumours in the pancreas known as insulinomas. The new method was presented online in the renowned medical journal Lancet on 25 July. The ...
Aug 20, 2013
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Using human pluripotent stem cells and DNA-cutting protein from meningitis bacteria, researchers from the Morgridge Institute for Research and Northwestern University have created an efficient way to target and repair defective ...
Aug 12, 2013
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