Genetics

Gene therapy treats chronic pain by dialing down sodium

Researchers at NYU College of Dentistry's Pain Research Center have developed a gene therapy that treats chronic pain by indirectly regulating a specific sodium ion channel, according to a new study published in the Proceedings ...

Neuroscience

Researchers describe a new way to visualize force-sensing neurons

A recent study by researchers at Texas Children's Hospital, Baylor College of Medicine, and Scripps Research Institute has discovered fluorescent dye FM 1-43 as an effective and versatile tool to visualize PIEZO2 ion channel ...

Neuroscience

How synaptic vesicles accumulate glutamate

In the brain, neurons communicate via neurotransmitters, which trigger electrical signals in downstream neurons by binding and activating specific receptors. Neurotransmitters are released through the fusion of synaptic vesicles, ...

Medical research

Beating seizures by jamming the cellular circuitry

Research at UC San Francisco has shown for the first time how the commonly prescribed seizure and pain medication, gabapentin, acts inside of cells, opening the door to new, more effective treatments for diseases like epilepsy ...

Neuroscience

A channel involved in pain sensation can also suppress it

Pain is good. It's the body's way to keep an animal from harming itself or repeating a dangerous mistake. But sometimes the debilitating sensation can get in the way. So evolution has devised ways to tamp that response down ...

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