In the era of Big Data, obtaining a huge amount of information is the easy part; knowing what to do with it is another story entirely. But now, researchers from Japan have reported that a new approach to analyzing data from ...
Sep 8, 2022
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The Aging journal has published a new research paper titled Isoform-specific effects of neuronal repression of the AMPK catalytic subunit on cognitive function in aged mice.
Mar 7, 2023
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Investigators at Weill Cornell Medicine have assembled the most comprehensive atlas to date of messenger RNA (mRNA) variants in the mouse and human brain. The atlas is an important new resource in understanding brain development, ...
Apr 9, 2024
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Proteomics is the study and analysis of proteins, including their structures, functions, interactions, and modifications within a biological system. Humans have approximately 20,000 genes that produce over a million different ...
Mar 29, 2023
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Medical University of South Carolina (MUSC) investigators report preclinical research showing that the tumor-promoting properties of neuropilin (NRP)-2 reside predominantly on isoform NRP2b, while NRP2a has the opposite effects ...
Jan 17, 2017
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A study led by the IBB-UAB has identified the molecular mechanism through which a protein carrying genetic mutations associated with limb-girdle muscular dystrophy type 1G accelerates its tendency to form amyloid fibrils ...
Jan 29, 2020
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A new research paper titled "Increased expression of BRD4 isoforms long (BRD4-L) and short (BRD4-S) promotes chemotherapy resistance in high-grade serous ovarian carcinoma" has been published in Genes & Cancer.
Sep 13, 2023
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Building a map of the complex human brain and its approximately 100 billion individual neurons is no easy task. As a precursor to tackling that monumental challenge, researchers have started off with something smaller and ...
Oct 11, 2021
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Memory B cells depend on autophagy for their survival, but the protein Rubicon is thought to hinder this process. Researchers from Osaka University have discovered a shorter isoform of Rubicon called RUBCN100, which enhances ...
Oct 2, 2023
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Rats are commonly used in nonclinical pharmaceutical studies to investigate the safety, efficacy and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via ...
Feb 21, 2019
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