The discovery of pluripotent stem cells, which have the ability to differentiate into the huge range of different cell lineages that make up the human body, signaled the start of a new era in biological science and medicine. ...
Dec 19, 2018
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The brain can discriminate over 1 trillion odors. Once entering the nose, odor-related molecules activate olfactory neurons. Neuron signals first accumulate at the olfactory bulb before being passed on to activate the appropriate ...
Oct 19, 2018
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How is it possible that so many different and highly specific neuron types arise in the brain? A mathematical model developed by researchers from the University of Basel's Biozentrum demonstrates that different variants of ...
Sep 26, 2018
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Medical University of South Carolina (MUSC) investigators report preclinical research showing that the tumor-promoting properties of neuropilin (NRP)-2 reside predominantly on isoform NRP2b, while NRP2a has the opposite effects ...
Jan 17, 2017
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It's not unusual for siblings to seem more dissimilar than similar: one becoming a florist, for example, another becoming a flutist, and another becoming a physicist.
Feb 11, 2016
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Alternative splicing, a process where a single gene can give rise to multiple different proteins via inclusion or exclusion of certain segments of the gene sequence, is known to occur in over 90% of human genes. This leads ...
Jun 12, 2024
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A new research paper titled "Increased expression of BRD4 isoforms long (BRD4-L) and short (BRD4-S) promotes chemotherapy resistance in high-grade serous ovarian carcinoma" has been published in Genes & Cancer.
Sep 13, 2023
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A new research paper was published in Oncotarget's, titled "Differential silencing of STAT3 isoforms leads to changes in STAT3 activation."
Apr 26, 2023
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Proteomics is the study and analysis of proteins, including their structures, functions, interactions, and modifications within a biological system. Humans have approximately 20,000 genes that produce over a million different ...
Mar 29, 2023
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The Aging journal has published a new research paper titled Isoform-specific effects of neuronal repression of the AMPK catalytic subunit on cognitive function in aged mice.
Mar 7, 2023
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