Arthritis & Rheumatism

Juvenile arthritis: why genetic risk is not in the genes

Scientists have been finding that genetic risk for many diseases lies primarily in noncoding parts of the genome, which used to be called "junk DNA," and not in the genes themselves. But that finding naturally begs more questions ...

Genetics

MicroRNA, the puppet master of the genome

We all know how irritating it is to have an inbox flooded with junk mail. Fortunately email providers these days contain filters to keep the junk mail at bay. As a result the junk mail folder tends to pile up with never-to-be-read ...

Genetics

Science of genome-sequencing marks 10 years

A decade after completion of the Human Genome Project on April 14, 2003, a top official of the National Institutes of Health surveyed the rarefied view from that mountaintop:

Genetics

Not dead yet: Junk DNA is back

A controversy at last: most of our DNA is junk, no it isn't, yes it is. Actually, I think it is – up to 90% really is junk.

Genetics

Chromatin marks the spot in search for disease pathways

In September 2012, the Encyclopedia of DNA Elements (ENCODE) Project Consortium, a multi-institution collaboration that included the Broad Institute, capped off nine years of research with a flurry of papers that characterized ...

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