Loss of function of the CRKL gene causes kidney and urinary tract defects in people with DiGeorge syndrome, a multinational team of scientists led by Columbia University Medical Center (CUMC) has found.
Jan 25, 2017
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Munich, Germany: The first drug to target a key enzyme that cancer cells need to keep them alive has shown that it is effective in controlling disease in patients with advanced kidney cancer when it is used in combination ...
Nov 30, 2016
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Research into kidney regeneration, an organ that has been extremely difficult to regenerate, has taken a great stride forward with research coming out of a collaboration between Kumamoto University, Japan and the National ...
Jun 6, 2016
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The best laid plans of mice and men are a bit different—at least when it comes to kidney development. Compared to a mouse, a human has nearly 100 times more nephrons, the functional units of the kidneys. Humans may owe ...
Mar 18, 2016
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Various research groups are collecting different types of cells and turning them into induced pluripotent stem (iPS) cells that can then generate diverse types of cells and tissues in the body. Now investigators have transplanted ...
Nov 19, 2015
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Investigators at Brigham and Women's Hospital (BWH) and the Harvard Stem Cell Institute (HSCI) have established a highly efficient method for making kidney structures from stem cells that are derived from skin taken from ...
Oct 16, 2015
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Kidney function can affect the potency and metabolism of drugs that are eliminated by the kidneys or other pathways, but little information is available on how to interpret the effects of kidney function on the benefits and ...
Feb 3, 2015
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Another mystery of the human body has been solved by scientists who have identified how a molecular motor essential for human development works. They have also pinpointed why mutations in genes linked to this motor can lead ...
Sep 9, 2014
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Nearly one-third of cases of Wilms tumor, a pediatric cancer of the kidney, are linked to a gene called Lin28, according to research from Boston Children's Hospital. Mice engineered to express Lin28 in their kidneys developed ...
Apr 13, 2014
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The researchers found virulent E. coli bacteria blocked a pathway that would normally protect the gut from infection. These infections are particularly serious in young children and can result in diarrhoea and other complications ...
Sep 11, 2013
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