Genetics

Two independent mechanisms are involved in tuberous sclerosis

The current idea about how tuberous sclerosis occurs places mTORC1, a protein complex that regulates cell metabolism, as the major driving force behind the disease. But according to a new study published in the Proceedings ...

Diseases, Conditions, Syndromes

New therapeutic targets for kidney fibrosis emerge

Chronic kidney disease is a global health concern, affecting about 10 percent of the world's population—and increasing in prevalence. A final, common pathway in chronic kidney disease is fibrosis. Just as fibrosis—or ...

Diseases, Conditions, Syndromes

Connecting the dots between heartburn drugs and kidney damage

(HealthDay)—Just because a medication is available over the counter doesn't mean it won't have side effects or pose other dangers. One example is PPIs, a popular type of heartburn medication that can harm the kidneys, especially ...

Cardiology

Zinc deficiency may play a role in high blood pressure

Lower-than-normal zinc levels may contribute to high blood pressure (hypertension) by altering the way the kidneys handle sodium. The study is published ahead of print in the American Journal of Physiology—Renal Physiology.

Diabetes

How to develop personalised diabetes treatment

Diabetes can lead to blindness, kidney failure, heart attack, stroke, lower limb amputation and premature death. It was the seventh leading cause of death in 2016, according to the World Health Organization. The Diabetes ...

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