A team of researchers at the University of Michigan Health Rogel Cancer Center has designed a molecule that impairs signaling mediated by two key drivers of cancer therapy resistance. The design and preclinical evaluation ...
Jul 29, 2024
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Cornell researchers have identified a switch that regulates inflammation caused by an immune response, a finding that could one day help clinicians control inflammation-related conditions such as autoimmune, cardiovascular ...
Jul 24, 2024
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A team of researchers from Penn State College of Medicine found a new target for treating diseases associated with human T-cell leukemia virus type 1 (HTLV-1). They determined that blocking a class of enzymes called kinases, ...
Jul 22, 2024
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"Recessive Dystrophic Epidermolysis Bullosa (RDEB) is the worst disease you've probably never heard of," says dermatology researcher Andrew South, Ph.D.. RDEB patients and their families know just how horrible it can be. ...
Jul 17, 2024
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In chemistry and biochemistry, a kinase is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific substrates, a process referred to as phosphorylation. Kinases are part of the larger family of phosphotransferases. Kinases are not to be confused with phosphorylases, which carry out phosphorolysis, the breaking of a bond using an inorganic phosphate group; or with phosphatases, which remove phosphate groups.
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