Oncology & Cancer

Tobacco use makes precancerous cells that fertilize cancer growth

Tobacco use causes a field of precancerous cells, increasing the risk of developing head & neck cancer. But exactly how this precancerous field influences cancer has been often overlooked. Now a University of Colorado Cancer ...

Oncology & Cancer

Tarloxotinib promising against NRG1-fusion cancers

A study by University of Colorado Cancer Center and Rain Therapeutics, Inc. presented at the American Association for Cancer Research (AACR) Annual Meeting 2019 shows that the clinical-stage drug, tarloxotinib, is active ...

Diseases, Conditions, Syndromes

Peptide shows promise for protecting kidneys from nephritis

A synthetic peptide appears to directly disrupt the destructive inflammation that occurs in nephritis, enabling the kidneys to better recover and maintain their important functions, investigators report.

Medical research

Researchers create a new molecule to treat heart failure

A group of researchers based in Brazil and the United States have developed a molecule that halts the progression of heart failure and improves the heart's capacity to pump blood. Rats with heart failure were treated for ...

Oncology & Cancer

Protein loss promotes cell migration

The protein STK17A (serine threonine kinase 17A) appears to play roles in various cancer types. It can be oncogenic or tumor suppressive, depending on the cancer, but its role in colorectal cancer has not been established.

Medications

Origin of resistance to lung-cancer drug discovered

Researchers at Kanazawa University report in Nature Communications that AXL, a protein belonging to the class of receptor tyrosine kinases, causes some lung cancer patients to have an intrinsic resistance to the drug osimertinib. ...

Diseases, Conditions, Syndromes

Tuberculosis—Inhibiting host cell death with immunotherapy

Tuberculosis treatment still entails the administration of several antibiotics over a period of months and is torturous for many patients. The pathogen's increasing multidrug resistance additionally complicates this lengthy ...

Oncology & Cancer

Molecular mechanisms behind AICAr drug; impact on ALL

AICAr (5-amino-4-imidazolecarboxamide riboside, also called Acadesine) has been found to inhibit cell proliferation and has cytotoxic potential for childhood acute lymphoblastic leukemia (ALL) cells. Much of the drug's cytotoxic ...

page 20 from 40