Genetics
Cancer drug could be repurposed to provide treatment for brain aneurysms
An important class of drug used to treat cancer patients could be used to treat brain aneurysms, according to new research published this week.
May 17, 2019
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Page 19 - News tagged with kinases
Neuroscience
AAN: Oral BTK inhibitor superior to placebo in multiple sclerosis
(HealthDay)—The selective Bruton's tyrosine kinase (BTK) inhibitor evobrutinib at a dose of 75 mg once daily is associated with fewer enhancing lesions during weeks 12 through 24 among patients with relapsing multiple sclerosis, ...
May 14, 2019
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Oncology & Cancer
At molecular level, cancer mutations echo Darwin's observations
There are more than 100 mutations of the protein behind the deadly brain cancer, glioblastoma, however an international research team has discovered something these mutations have in common. The new understanding could lead ...
Apr 30, 2019
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Oncology & Cancer
Reasons for TKI discontinuation ID'd in chronic myeloid leukemia
(HealthDay)—For patients with chronic myeloid leukemia (CML), tyrosine kinase inhibitor (TKI) therapy can be safely discontinued and yields high rates of treatment-free remission (TFR), according to a study published online ...
Apr 16, 2019
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Medical research
Researchers succeed at removing some types of pancreatic cancer in animal models
Researchers from the Experimental Oncology Group, led by Mariano Barbacid at the Spanish National Cancer Research Centre (CNIO), have published in Cancer Cell the results of a study that shows full regression of advanced ...
Apr 12, 2019
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Medical research
The protein p38-gamma identified as a new therapeutic target in liver cancer
An enzyme involved in cell stress responses could become a new pharmacological target in the treatment of liver cancer, a disease that currently has few available treatment options. The research team at the Centro Nacional ...
Apr 10, 2019
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Oncology & Cancer
Adenosine kinase deficiency makes liver more susceptible to carcinogen
A new study has shown that reduced adenosine kinase expression (ADK) in the liver can make it more susceptible to carcinogenic damage and the development of liver cancer. Combined results from the study of human liver cancer ...
Apr 10, 2019
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Oncology & Cancer
Quashing the resistance: MicroRNA regulates drug tolerance in subset of lung cancers
Relapse of disease following conventional treatments remains one of the central problems in cancer management, yet few therapeutic agents targeting drug resistance and tolerance exist. New research conducted at the Cancer ...
Apr 8, 2019
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Oncology & Cancer
Ibrance approval expanded to include men with breast cancer
(HealthDay)—U.S. Food and Drug Administration approval of Ibrance (palbociclib) capsules has been widened to include men with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced or metastatic ...
Apr 6, 2019
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Medical research
Vitamin B12 identified as the inhibitor of a key enzyme in hereditary Parkinson's disease
Iban Ubarretxena, an Ikerbasque researcher and director of the Biofisika Institute (CSIC-UPV/EHU), participated in a study that identified new inhibitors that could be used to develop drugs to combat Parkinson's. The research ...
Apr 3, 2019
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