Neuroscience

In the quest for a TBI therapy, astrocytes may be the bull's-eye

Growing evidence suggests that traumatic brain injury (TBI) is an important risk factor for developing Alzheimer's disease and dementia. But to date, effective therapies aren't available for preventing or treating TBI-induced ...

Immunology

ATP-hydrolyzing ectoenzyme E-NTPD8 attenuates colitis

The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system. An imbalance of microbial metabolites has been implicated ...

Alzheimer's disease & dementia

Beige fat 'indispensable' in protecting the brain from dementia

Beige is considered a calming paint color, and scientists have new evidence that beige fat has a similar impact on the brain, bringing down the inflammation associated with the more common white fat and providing protection ...

Medical research

Protecting against atherosclerosis at the molecular level

Atherosclerosis is the result of a buildup of lipids in the inner walls of blood vessels, and is a major cause of heart disease and stroke. In a new study, researchers from the University of Tsukuba discovered a novel role ...

Neuroscience

Neural crest cell migration in Hirschsprung disease

Ankush Gosain, MD, Ph.D., of Le Bonheur Children's Hospital and the University of Tennessee Health Science Center has focused his research on determining the mechanisms underlying abnormal development of the enteric nervous ...

Neuroscience

Potential target identified for migraine therapy

Migraines affect millions of people worldwide, often lasting days and severely disrupting lives. More than simply super-intense headaches, some migraines actually result from pathological excitation of neurons in the brain. ...

page 1 from 11