Medical research

Protecting against atherosclerosis at the molecular level

Atherosclerosis is the result of a buildup of lipids in the inner walls of blood vessels, and is a major cause of heart disease and stroke. In a new study, researchers from the University of Tsukuba discovered a novel role ...

Neuroscience

Neural crest cell migration in Hirschsprung disease

Ankush Gosain, MD, Ph.D., of Le Bonheur Children's Hospital and the University of Tennessee Health Science Center has focused his research on determining the mechanisms underlying abnormal development of the enteric nervous ...

Neuroscience

Potential target identified for migraine therapy

Migraines affect millions of people worldwide, often lasting days and severely disrupting lives. More than simply super-intense headaches, some migraines actually result from pathological excitation of neurons in the brain. ...

Neuroscience

Boosting energy levels within damaged nerves may help them heal

When the spinal cord is injured, the damaged nerve fibers—called axons—are normally incapable of regrowth, leading to permanent loss of function. Considerable research has been done to find ways to promote the regeneration ...

Medical research

How signalling proteins affect wound healing

What do a scraped knee, a paper cut, or any form of surgery have in common? The short answer is a wound in need of healing—but the long answer lies in a series of biological activities that allow tissues to repair themselves.

Cardiology

A kinase identified as possible target to treat heart failure

An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies. Failing human hearts showed reduced amounts of this kinase, and preclinical ...

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