Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have identified how an enzyme called PKCĪ¶ suppresses prostate tumor formation. The finding, which also describes a molecular chain of events that ...
Apr 1, 2013
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In recent debate over the FDA's approval of the Alzheimer's drug aducanumab, we've heard a lot about the "amyloid hypothesis." In that context, it's refreshing to learn about a model of Alzheimer's neurodegeneration that ...
Jun 29, 2021
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Atherosclerosis is the result of a buildup of lipids in the inner walls of blood vessels, and is a major cause of heart disease and stroke. In a new study, researchers from the University of Tsukuba discovered a novel role ...
Dec 21, 2020
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An unexplored kinase in heart muscle cells may be a good target to treat heart failure, a disease that is only incrementally delayed by existing therapies. Failing human hearts showed reduced amounts of this kinase, and preclinical ...
Oct 31, 2019
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Inherited diseases of the eye account for at least 2 million cases of blindness worldwide. A few hundred genes that cause eye disease have been identified, but in many cases the cause is unknown because not all eye disease ...
Feb 20, 2019
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A new study provides surprising evidence that people with narcolepsy have an increased number of neurons that produce histamine, suggesting that histamine signaling may be a novel therapeutic target for this potentially disabling ...
Jun 3, 2013
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A collaboration between researchers at the School of Biochemistry and Immunology and the Department of Microbiology at Trinity College Dublin has identified a mechanism by which the bacterium Staphylococcus aureus (S. aureus) ...
Dec 27, 2012
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No cure exists for frontotemporal dementia, which strikes between the ages of 40 and 64 and accounts for at least one in four cases of early-onset dementia. Caused by the death of cells in the front and sides of the brain, ...
Sep 21, 2011
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Scripps Research Institute scientists have discovered new elements of the blood clot-formation process. The findings could lead to better drugs for preventing heart attacks and other clot-related conditions.
Jun 13, 2011
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Researchers at the University of North Carolina at Chapel Hill School of Medicine have shown in an animal study that transplantation of adult stem cells enriched with a bone-regenerating hormone can help mend bone fractures ...
Jun 5, 2011
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