Premature ovarian aging (POA) refers to an early decline in ovarian function; it is the main cause of infertility in older women and is characterized by a markedly reduced ovarian reservoir. An interesting review summarized ...
Sep 5, 2022
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Glaucoma is an irreversible blinding eye disease characterized by progressive ganglion cell death. To date, IOP control has been almost the only clinical option for the treatment of POAG. However, visual field damage continues ...
Aug 26, 2022
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High-fat diet (HFD) feeding in mice promotes induction of aldose reductase (AR) activity, expression, and senescence of adipocytes in subcutaneous adipose tissue (scAT), according to a new study in Obesity journal.
Jul 27, 2022
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Innate immunity is activated when the pattern recognition receptors (PRRs) recognize pathogen-associated molecular patterns (PAMPs). A research team from Kanazawa University has shown that a liver-derived secretory protein ...
Jul 15, 2022
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Research into the causes of type 1 diabetes often focuses on the autoimmune response, where the immune system destroys pancreatic islet beta cells that produce insulin. A new study by scientists at the University of Chicago ...
Jun 28, 2022
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Growing evidence suggests that traumatic brain injury (TBI) is an important risk factor for developing Alzheimer's disease and dementia. But to date, effective therapies aren't available for preventing or treating TBI-induced ...
Feb 10, 2022
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A devastating genetic disease called CDKL5 deficiency disorder (CDD), which strikes in early childhood, may be significantly treatable even in adulthood, a new study from the Perelman School of Medicine at the University ...
Oct 15, 2021
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The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system. An imbalance of microbial metabolites has been implicated ...
Sep 20, 2021
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Beige is considered a calming paint color, and scientists have new evidence that beige fat has a similar impact on the brain, bringing down the inflammation associated with the more common white fat and providing protection ...
Aug 10, 2021
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In recent debate over the FDA's approval of the Alzheimer's drug aducanumab, we've heard a lot about the "amyloid hypothesis." In that context, it's refreshing to learn about a model of Alzheimer's neurodegeneration that ...
Jun 29, 2021
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