Neuroscience

Oligodendrocytes induce motor neuron death in ALS

A first-of-its-kind oligodendrocyte in vitro model shows that human cells normally supportive of motor neuron function play an active role in amyotrophic lateral sclerosis pathogenesis – and this discovery may point the ...

Neuroscience

Smoking tied to shorter survival with ALS

(HealthDay)—Smoking may speed progression of Lou Gehrig's disease and shorten the lives of those with the fatal illness, new research suggests.

Neuroscience

Research to delay motor neuron loss

University of Queensland researchers have identified a potential treatment to delay motor neuron loss and symptoms in the inevitably fatal motor neuron disease (MND).

Neuroscience

When silencing phantom noises is a matter of science

With a clever approach, researchers point to the first gene that could be protective of tinnitus—that disturbing ringing in the ear many of us hear, when no sound is present.

Neuroscience

Progress in the fight against ALS

A Brandeis research group has found a way to repair a vital signaling mechanism in fruit flies with symptoms of ALS. As a result, dying motor neurons regained health and the once paralyzed flies regained partial motion.

Neuroscience

Study shows how mutations disrupt ALS-linked protein

In amyotrophic lateral sclerosis, aggregates of the protein TDP-43 are almost always found in afflicted neurons and glial cells. Meanwhile, about 50 ALS-linked mutations are known to affect a particular region of TDP-43. ...

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