Degeneration of the axon and synapse, the slender projection through which neurons transmit electrical impulses to neighboring cells, is a hallmark of some of the most crippling neurodegenerative and brain diseases such as ...
Jun 7, 2012
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Researchers at the Babraham Institute and University of Massachusetts Medical School in the United States have developed a new model to study motor neuron degeneration and have used this to identify three genes involved in ...
Aug 6, 2015
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New research shows environmental pollutants could affect the chances a person will develop amyotrophic lateral sclerosis, or ALS.
May 9, 2016
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Recent research from Houston Methodist Hospital showed that a new immunotherapy was safe for patients with ALS and also revealed surprising results that could bring hope to patients who have this relentlessly progressive ...
May 21, 2018
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Scientists have discovered how certain forms of motor neuron disease begin and progress at cellular and molecular levels, revealing potential new ways to slow down or even stop this process. The team are already working closely ...
May 30, 2017
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Amyotrophic lateral sclerosis (ALS) is an intractable neurological disease. Aging is a risk factor for the accumulation of TDP-43 (transduction responsive region DNA-binding protein of 43kDa) in the motor cortex. TDP-43 is ...
Sep 29, 2021
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Muscles waste as a result of not being exercised enough, as happens quickly with a broken limb that has been immobilized in a cast, and more slowly in people reaching an advanced age. Muscle atrophy, how clinicians refer ...
Nov 14, 2022
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Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43. The study, which will be published ...
Aug 4, 2021
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The Stentrode is a device that is placed inside a blood vessel of the brain located in an area that controls movement (motor cortex). It is the only investigational technology of its kind that does not require open brain ...
Apr 8, 2019
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(Medical Xpress)—A Purdue University biochemist has determined the function of a gene that when mutated leads to a genetic variation of amyotrophic lateral sclerosis, or Lou Gehrig's disease.
Dec 11, 2012
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