A new paper in Annals of Neurology describes the approach, structure, and launch of the HEALEY ALS Platform Trial—the first platform trial for amyotrophic lateral sclerosis (ALS)—designed to accelerate the development ...
Feb 28, 2022
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Researchers on Mayo Clinic's Florida campus have identified key differences between patients with sporadic amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and those with the most common genetic form of ALS, a ...
Jul 20, 2015
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Amyotrophic lateral sclerosis, or ALS, attacks nerve cells known as motor neurons in the brain and spinal cord, gradually leading to paralysis. The loss of function of an important gene, C9orf72, may affect communication ...
Jun 30, 2021
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A team of researchers at Mayo Clinic and The Scripps Research Institute in Florida have developed a new therapeutic strategy to combat the most common genetic risk factor for the neurodegenerative disorders amyotrophic lateral ...
Aug 14, 2014
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Amyotrophic lateral sclerosis is a devastating neurodegenerative disease that affects about 1 in 50,000 people. Well-known people who suffered from ALS include baseball player Lou Gehrig, who lived two years after he was ...
Apr 13, 2022
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(HealthDay)—There is a linear correlation for physical activity (PA) with amyotrophic lateral sclerosis (ALS), according to a study published online April 23 in the Journal of Neurology, Neurosurgery & Psychiatry.
Apr 24, 2018
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The ALS-related protein TDP-43 takes the first steps toward pathologic aggregation as part of its normal function, according to a new study publishing in the Open Access journal PLOS Biology on Jan. 6, 2016. The study, by ...
Jan 6, 2016
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Researchers including bioinformaticians from the Helmholtz Zentrum München and Ludwig-Maximilians-Universität München organize crowdsourcing challenge to identify new algorithms that will expedite the search for effective ...
Nov 4, 2014
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Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks muscle-controlling nerve cells – motor neurons – in the brain, brainstem and spinal cord, leading to progressive weakness and eventual ...
Oct 30, 2014
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(HealthDay)—Smoking may speed progression of Lou Gehrig's disease and shorten the lives of those with the fatal illness, new research suggests.
Sep 22, 2016
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