Diseases, Conditions, Syndromes

INRS takes aim at dreaded tropical disease leishmaniasis

Leishmania is a microorganism that enters the human body via a sandfly bite. The parasite allows itself to be swallowed up by white blood cells to advance its life cycle. The disease threatens the health of over 500 million ...

Immunology

How chronic infections can outsmart the immune system

Professor Simona Stäger and her team at INRS have discovered a mechanism that causes the body to sabotage its own defenses against infection by visceral leishmaniasis, a fatal tropical disease. This discovery could help ...

Diseases, Conditions, Syndromes

Discovery of a new potential treatment for visceral leishmaniasis

A new preclinical candidate drug with the potential to treat visceral leishmaniasis, one of the world's major neglected diseases, has been discovered through a close collaboration between the University of Dundee, GSK and ...

Diseases, Conditions, Syndromes

Team advances in developing vaccine for cutaneous leishmaniasis

A research team at The University of Texas at El Paso is one step closer to developing an effective human vaccine for cutaneous leishmaniasis, a tropical disease found in Texas and Oklahoma, and affecting some U.S. troops ...

Diseases, Conditions, Syndromes

Research identifies potential targets for treatment of leishmaniasis

Brazilian researchers at the University of São Paulo's Bioscience Institute (IB-USP) are starting to unravel the molecular mechanisms by which the parasite that causes cutaneous leishmaniasis circumvents the host organism's ...

Diseases, Conditions, Syndromes

New information on a major player in chronic visceral leishmaniasis

In an article in the latest issue of PLOS Pathogens, INRS professor Simona Stäger and her team show how the parasite Leishmania donovani uses a physiological response to low oxygen levels (hypoxia) to establish a chronic ...

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