Patients with X-linked severe combined immunodeficiency disorder (SCID-X1), sometimes called "bubble boy disease," are born with a defective gene that prevents them from producing immune cells. Gene therapy from St. Jude ...
Oct 6, 2023
0
26
A new approach from Penn Medicine researchers could cut the time it takes to alter patients' immune cells for infusion back into the body to find and attack cancer. The cell manufacturing process for this type of immunotherapy ...
Mar 29, 2022
0
133
Researchers at Children's Hospital of Philadelphia (CHOP) have developed a gene therapy vector for blood disorders like sickle cell disease and beta-thalassemia that is potentially safer and more effective than those currently ...
Jan 29, 2021
0
69
Before gene therapy can be used to treat renal diseases, delivery of therapeutic genes to the kidney must become much more efficient. A novel approach in which three different gene delivery vectors were injected intravenously ...
Dec 31, 2019
0
39
Gene therapy has broadened the treatment possibilities for those with immune system deficiencies and blood-based conditions, such as sickle cell anemia and leukemia. These diseases, which once would require a bone marrow ...
Oct 18, 2019
0
154
A team of researchers affiliated with several institutions in the U.S., working with biotech firm Lentigen, has found that duoCAR-T cells they created were effective against HIV in human mouse models. In their paper published ...
A team of researchers from institutions in Italy and the U.S., in conjunction with several corporate entities, has found that adding a protein to lentiviral vectors can protect them from an immune system attack. In their ...
