Overweight & Obesity

Gut-brain connection helps explain how overeating leads to obesity

Eating extra servings typically shows up on the scale later, but how this happens has not been clear. A new study published today in the Journal of Clinical Investigation by a multi-institutional team led by researchers at ...

Medical research

Study reveals biology of leptin, the hunger hormone

In a new study, Yale researchers offer insight into leptin, a hormone that plays a key role in appetite, overeating, and obesity. Their findings advance knowledge about leptin and weight gain, and also suggest a potential ...

Neuroscience

Satiety in 3-D

Many overweight people lack the feeling of being full. It was long thought that this was due to the disrupted transport of the satiety hormone leptin to the brain. That is not the case, as a group of scientists from Helmholtz ...

Medical research

A new drug to help young patients with genetic obesity

In a new study, researchers from the Institute for Experimental Pediatric Endocrinology of the Charité - Universitätsmedizin Berlin have successfully treated patients whose obesity is caused by a genetic defect. Aside from ...

Medical research

Obese inducing brain mechanism

Leptin is an adipocyte-derived hormone that stimulates hypothalamic neurons to strongly inhibit food intake. Leptin signaling in the hypothalamus, a part of the mid-brain, thus plays a crucial role in the regulation of body ...

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