Oncology & Cancer
Cancer's dangerous renovations to our chromosomes revealed
Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, University of Virginia researchers have revealed.
Oct 27, 2020
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Page 29 - News tagged with leukemia cells
Oncology & Cancer
New insights into the genetic basis of leukemia
Acute myeloid leukemia (AML) is a malignant disease of the hematopoietic system that originates from immature precursors of red blood cells, platelets and part of the white blood cells. While in healthy people the multiplication ...
Jan 24, 2023
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Oncology & Cancer
Antibody-guided drug works against acute lymphoblastic leukemia
An antibody packaged with a potent chemotherapy drug to selectively destroy acute lymphoblastic leukemia (ALL) cells eradicated or greatly reduced the disease for 61 percent of 46 patients in a phase II study. It will be ...
May 23, 2011
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Oncology & Cancer
Study defines a possible target for future treatments for a deadly form of the disease
Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have discovered that a protein produced by a cancer gene leads to the development of a deadly, late-stage form of prostate ...
Apr 1, 2016
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Medical research
Study finds leukemia cells are 'bad to the bone'
University of Rochester Medical Center researchers have discovered new links between leukemia cells and cells involved in bone formation, offering a fresh perspective on how the blood cancer progresses and raising the possibility ...
Jan 26, 2012
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Oncology & Cancer
High response rates, long-term remissions in Penn trials of personalized cell therapy
Ninety-three percent of pediatric patients (55 of 59) with relapsed/refractory acute lymphoblastic leukemia (ALL) went into remission after receiving an investigational therapy made from their own immune cells, with continuous ...
Dec 7, 2015
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Oncology & Cancer
Scientists modify CAR-T cells to target multiple sites on leukemia cells
In a new pre-clinical study published this week in the journal Leukemia, the research team of Children's Hospital Los Angeles investigator Hisham Abdel-Azim, MD, MS, worked with colleagues to engineer T-cells to identify ...
Apr 1, 2020
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Oncology & Cancer
New culprit discovered in T-cell acute lymphoblastic leukemia
A new study published in the journal Nature Medicine by NYU Cancer Institute researchers, shows how the cancer causing gene Notch, in combination with a mutated Polycomb Repressive Complex 2 (PRC2) protein complex, work together ...
Jan 12, 2012
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Oncology & Cancer
Cell signaling targets in leukemia
Mutations in the enzyme IDH (isocitrate dehydrogenase) are found in 15–20% of acute myeloid leukemia (AML) cases. IDH mutations have been shown to impact cellular differentiation and DNA and histone methylation, but little ...
Dec 13, 2021
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Oncology & Cancer
Leukemia thwarted by cutting off link to environmental support
A new study by researchers at University of California, San Diego School of Medicine reveals a protein's critical - and previously unknown—role in the development and progression of acute myeloid leukemia (AML), a fast-growing ...
Jul 23, 2015
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