Doctors who treat children with the most common form of childhood cancer – acute lymphoblastic leukemia – are often baffled at how sometimes the cancer cells survive their best efforts and the most powerful modern ...
May 18, 2011
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Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between ...
Apr 8, 2024
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Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have devised an innovative approach to target and destroy hard-to-kill leukemia stem cells. The journal Blood ...
Feb 26, 2024
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New research from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and collaborating organizations has identified a next-generation BTK degrader that could help overcome treatment ...
Feb 1, 2024
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A discovery by a QIMR Berghofer-led team of international scientists has potentially unlocked an entirely new approach to targeting the blood cancer acute myeloid leukemia, bringing hope to patients who are no longer responding ...
Oct 30, 2023
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In a world first, Newcastle researchers have discovered the mechanisms acute myeloid leukemia (AML) cells use to produce "free radicals"—the byproduct of a cell process that aggressively fuels the growth of cancer cells ...
Mar 29, 2023
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A new targeted drug has not only sparked remissions in patients with a common form of leukemia but also induced the cancer cells to reveal one of their schemes for resisting the drug, investigators at Dana-Farber Cancer Institute ...
Mar 15, 2023
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Building a new precision cancer treatment comes with no shortage of scientific challenges. Now, a group of University of Florida researchers have made a significant discovery in the effort to develop potent, highly targeted ...
Feb 20, 2023
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As a child, Lynn Aureli didn't know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain the cancer's lack of response to chemotherapy. Nor was ...
Jan 27, 2023
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Patients with acute myeloid leukemia, the most common type of adult blood cancer, show large-scale genomic mutations and altered DNA folding patterns that could help identify potential therapeutic targets, according to a ...
Oct 28, 2022
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