Oncology & Cancer

An antibody-drug combo to combat cancer

Leukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at Tokyo Medical and Dental University (TMDU) describe an ingenious strategy against chronic myelomonocytic ...

Oncology & Cancer

Targeted elimination of leukemic stem cells

Leukemia is caused by leukemic stem cells which are resistant to most known therapies. Relapses are also due to this resistance. Leukemic stem cells arise from normal blood-forming (hematopoietic) stem cells. Because they ...

Medications

Metoclopramide inhibits proliferation of leukemia stem cells

A research team at Inselspital, Bern University Hospital and the University of Bern has identified and tested the use of an agent that can effectively inhibit the proliferation of leukemia stem cells. Metoclopramide (MPR), ...

Oncology & Cancer

Global trial reveals life saving drug for acute myeloid leukemia

A landmark paper published today in the New England Journal of Medicine describes the results from a global trial across 148 sites in 23 countries, showing a 30 percent improvement in survival in patients with acute myeloid ...

Medical research

New therapeutic approach against leukemia

Leukemia frequently originates from the so-called leukemic stem cell, which resides in a tumor promoting and protecting niche within the bone marrow. Scientists from the Max Planck Institute of Biochemistry in Martinsried, ...

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