The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia
A new role for cohesin in regulating alternative splicing has been identified, providing insights into splicing mutations in human disease.
A new role for cohesin in regulating alternative splicing has been identified, providing insights into splicing mutations in human disease.
Targeted drugs have been developed to supplement chemotherapy in the treatment of cancer. These drugs only affect cancer cells, leaving healthy cells alone. Venetoclax is a new targeted therapy option for the treatment of ...
Feb 23, 2023
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Leukemia, a type of blood cancer, affected around 2.3 million people around the world in 2015. Acute myeloid leukemia (AML)—a particularly aggressive disease—generally starts in the bone marrow, when stem cells cannot ...
Jan 31, 2023
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As a child, Lynn Aureli didn't know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain the cancer's lack of response to chemotherapy. Nor was ...
Jan 27, 2023
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High doses of vitamin D alleviated symptoms for patients with toxic erythema of chemotherapy (TEC) significantly faster than current treatments, according to a Northwestern Medicine study published in JAMA Dermatology.
Jan 18, 2023
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Prior to allogeneic stem cell transplantation for the treatment of acute myeloid leukemia (AML), complete remission is currently still considered the gold standard of care.
Dec 12, 2022
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Leukemia is often the result of the disruption to the fine balance in blood cell production where new cells are manufactured and old blood cells die.
Jul 5, 2022
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Genetically engineered immune cells successfully target the specific cancer cells that may be responsible for relapse of acute myeloid leukemia (AML), a type of blood cancer, and proved effective in animal models of the disease, ...
Jun 2, 2022
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Cancer researchers at the University Medical Center Schleswig-Holstein (UKSH), Campus Kiel, and at the Medical Faculty of Kiel University have described approaches for improved therapy of adult blood cancer patients in a ...
Apr 21, 2022
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For patients with acute lymphoblastic leukemia with resistance to C19 CAR T-cell therapy, resistance mechanisms that can be detected prior to treatment have been identified, according to a study presented at the annual meeting ...
Apr 12, 2022
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