Cancer

Obesity linked to adverse events in children with leukemia

(HealthDay)—For children with acute lymphoblastic leukemia (ALL), obesity is associated with an increased risk for adverse events during premaintenance chemotherapy, according to a study published in the February issue ...

Cancer

New therapy for aggressive blood cancer discovered

Researchers at Vetmeduni Vienna and Ludwig Boltzmann Institute for Cancer Research have identified a new therapeutic strategy foR acute myeloid leukemia. They found that the activity of the mutated oncogenic protein C/EBPα ...

Cancer

Molecular mechanisms behind AICAr drug; impact on ALL

AICAr (5-amino-4-imidazolecarboxamide riboside, also called Acadesine) has been found to inhibit cell proliferation and has cytotoxic potential for childhood acute lymphoblastic leukemia (ALL) cells. Much of the drug's cytotoxic ...

Cancer

Cancer causes premature ageing

Leukaemia promotes premature ageing in healthy bone marrow cells—according to new research from the University of East Anglia.

Medications

Finding second hits to knock out leukemia

Many new anti-cancer drugs inhibit proteins that are essential for the proliferation of cancer cells. One example is ibrutinib, an innovative therapy for chronic lymphocytic leukemia first approved in 2014. Chronic lymphocytic ...

Cancer

Understanding the emergence of leukemia

Acute T-cell lymphoblastic leukemia is a rare type of blood cancer that affects mostly children. This blood cancer appears from the precursor cells that produce T lymphocytes (a type of white blood cells). A new study from ...

Cancer

New treatment approach for leukemia

The BCR/ABL gene, which does not occur among healthy people, has been shown to be a causative agent in the pathogenesis of B-cell acute lymphocytic leukemia. The gene causes white blood cells to become leukemia cells that ...

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Leukemia

Leukemia (British English: leukaemia) (Greek leukos λευκός, "white"; aima αίμα, "blood") is a cancer of the blood or bone marrow and is characterized by an abnormal proliferation (production by multiplication) of blood cells, usually white blood cells (leukocytes). Leukemia is a broad term covering a spectrum of diseases. In turn, it is part of the even broader group of diseases called haematological neoplasms.

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