Looking around us, we can see that people age at different rates. But what about inside? Do all cells age in the same way? And does the location of a cell in the organ make a difference to the aging process?
Nov 10, 2023
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Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals' genetic ancestry. PKU causes an amino acid—called phenylalanine (Phe)—to build ...
Nov 2, 2023
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Psoriasis—a chronic skin condition—is not caused or spread by spontaneous genetic mutations in the skin, new research suggests.
Oct 26, 2023
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Researchers at University of California San Diego have discovered a process in which liver cells share molecules via vesicle exchange in order to multiply under conditions that would ordinarily suppress cell proliferation. ...
Oct 17, 2023
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Giving living donor liver transplant recipients an infusion of immune cells derived from their donor a week before transplantation is feasible, safe—and may lead to recipients being successfully weaned off immunosuppressant ...
Oct 11, 2023
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Liver fibrosis is associated with various liver injuries, including viral infection, inflammation, excess alcohol consumption, and metabolic dysfunction. More importantly, the number of patients with metabolic dysfunction-associated ...
Oct 10, 2023
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Cancer cells are chameleons. They completely change their metabolism to grow continuously. University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote ...
Oct 6, 2023
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Memory B cells depend on autophagy for their survival, but the protein Rubicon is thought to hinder this process. Researchers from Osaka University have discovered a shorter isoform of Rubicon called RUBCN100, which enhances ...
Oct 2, 2023
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A team of researchers has uncovered a previously unknown compensatory mechanism found in liver disease. If Kupffer cells (KCs), a specific kind of immune cells found in the liver, become impaired by tissue scarring, immune ...
Sep 28, 2023
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A severe form of fatty liver disease called nonalcoholic steatohepatitis (NASH) is the leading cause of liver transplantation, but there are few treatment options and currently no medications. In a new study, Yale researchers ...
Sep 27, 2023
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