FDA approves first nonhormonal drug to ease menopause hot flashes
The U.S. Food and Drug Administration on Friday approved the first nonhormonal medication aimed at easing menopause hot flashes.
May 15, 2023
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The U.S. Food and Drug Administration on Friday approved the first nonhormonal medication aimed at easing menopause hot flashes.
May 15, 2023
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Duke Health researchers have identified the cause of an inherited metabolic disease common among people with Lumbee and other Native American heritage, overturning decades of settled science and pointing to new, more effective ...
Apr 19, 2023
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Liver cancer is the third leading cause of cancer death and the sixth most common cancer type worldwide. Major risk factors include environmental and metabolic stressors, such as obesity, viral hepatitis and steatohepatitis ...
Apr 12, 2023
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A recently developed amino acid compound successfully treats nonalcoholic fatty liver disease in non-human primates—bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing ...
Apr 10, 2023
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Pain relievers you buy at the store may be one of the first things you reach for when you hurt yourself, have a headache or backache, or feel discomfort due to some other nagging ailment that doesn't require a visit to the ...
Mar 29, 2023
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Scientists have identified an autoinflammatory disease caused by mutations in the LYN gene, an important regulator of immune responses in health and disease. Named Lyn kinase-associated vasculopathy and liver fibrosis (LAVLI), ...
Mar 28, 2023
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SARS-CoV-2 infects and causes damage to multiple organs in COVID-19 patients. In particular, liver damage has been associated with COVID-19 severity. However, an understanding of the liver pathophysiology of these patients ...
Mar 8, 2023
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"Are nonstick pans toxic"? "Can aluminum cookware cause dementia?" "Are my scratched pans still safe?" That's just a sample of a few worrying headlines about the safety of our pots and pans recently.
Feb 22, 2023
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In hepatic steatosis, hepatocytes "die," resulting in liver damage. Severe steatosis increases hepatocellular deaths, thus aggravating liver damage. The mechanism is unclear. Using mice, we show that mild steatosis causes ...
Feb 15, 2023
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A mutant or damaged gene may be a cause of a severe, mysterious form of nonalcoholic fatty liver disease, University of Illinois Urbana-Champaign researchers have found. Mice and human liver cells lacking the SRSF1 gene show ...
Feb 9, 2023
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Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents when taken in overdoses and sometimes even when introduced within therapeutic ranges may injure the organ. Other chemical agents such as those used in laboratories and industries, natural chemicals (e.g. microcystins) and herbal remedies can also induce hepatotoxicity. Chemicals that cause liver injury are called hepatotoxins.
More than 900 drugs have been implicated in causing liver injury and it is the most common reason for a drug to be withdrawn from the market. Chemicals often cause subclinical injury to liver which manifests only as abnormal liver enzyme tests. Drug induced liver injury is responsible for 5% of all hospital admissions and 50% of all acute liver failures.
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