US approves gene therapy treatment for hemophilia
Pharmaceutical giant Pfizer has received US approval for a gene therapy against a form of hemophilia, a rare and inherited blood clotting disorder, the company said Friday.
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Pharmaceutical giant Pfizer has received US approval for a gene therapy against a form of hemophilia, a rare and inherited blood clotting disorder, the company said Friday.
15 hours ago
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Chemists invented PFAS in the 1930s to make life easier: Nonstick pans, waterproof clothing, grease-resistant food packaging and stain-resistant carpet were all made possible by PFAS. But in recent years, the growing number ...
Apr 22, 2024
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Innovative carbon beads, invented by researchers at UCL, reduce bad bacteria and inflammation in animal models, which are linked to liver cirrhosis and other serious health issues.
Apr 14, 2024
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Two deaths and more than 100 hospitalizations have been linked to a growing health scare in Japan around dietary supplements meant to lower cholesterol, the government said Wednesday.
Mar 27, 2024
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Fatty liver, which can lead to liver damage and disease, can occur from both overeating and starvation. Now, new research shows how naturally starvation-resistant cavefish, unlike other animals, are able to protect their ...
Mar 18, 2024
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Liver disease specialists at the University of Chicago Medicine will soon begin prescribing a first-of-its-kind drug for treating advanced metabolic dysfunction-associated steatotic liver disease (MASLD)—formerly known ...
Mar 15, 2024
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The US Food and Drug Administration (FDA) on Thursday approved the first medication for people with a severe type of non-alcoholic fatty liver disease.
Mar 15, 2024
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It's estimated that 2 to 3 million people in the U.S. are living with the hepatitis C virus, and hundreds of thousands of them are undiagnosed. That's primarily because it tends to be asymptomatic in the initial stages until ...
Mar 12, 2024
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A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell ...
Dec 27, 2023
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The NHS spends a lot of time and money looking after people who smoke, or drink too much or don't do enough exercise. Hospital admissions and treatments are an expensive business.
Dec 14, 2023
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Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents when taken in overdoses and sometimes even when introduced within therapeutic ranges may injure the organ. Other chemical agents such as those used in laboratories and industries, natural chemicals (e.g. microcystins) and herbal remedies can also induce hepatotoxicity. Chemicals that cause liver injury are called hepatotoxins.
More than 900 drugs have been implicated in causing liver injury and it is the most common reason for a drug to be withdrawn from the market. Chemicals often cause subclinical injury to liver which manifests only as abnormal liver enzyme tests. Drug induced liver injury is responsible for 5% of all hospital admissions and 50% of all acute liver failures.
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