Health

Drinking and your health: A reality check

(HealthDay)—The Mediterranean diet consistently tops the list of food plans that convey health benefits, and one reason many people like it is that it allows moderate amounts of red wine. But there's no definitive proof ...

Medical research

MANF identified as a rejuvenating factor in parabiosis

Older mice who are surgically joined with young mice in order to share a common bloodstream get stronger and healthier, making parabiosis one of the hottest topics in age research. Publishing in Nature Metabolism, researchers ...

Diseases, Conditions, Syndromes

Reducing unnecessary medication for hepatitis B patients

Not all chronic hepatitis B (HBV) patients require lifelong treatment; but the risks of blindly withdrawing treatment can be severe. However, there's little consensus on which patients can be safely discontinued from treatment, ...

Diseases, Conditions, Syndromes

Young plasma restores aged livers

A recent study published in The FASEB Journal examined the effect of young plasma on aged livers, and livers' sensitivity to ischemia reperfusion injury (IRI) in experimental animals. IRI occurs when blood flow to an organ ...

Medical research

Body clock link to steroids discovered

Professor David Ray, from The University of Manchester, lead the research which found that out of 752 genes which regulate lungs in mice, 230 genes work only in the day and only 197 at night.

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Hepatotoxicity

Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents when taken in overdoses and sometimes even when introduced within therapeutic ranges may injure the organ. Other chemical agents such as those used in laboratories and industries, natural chemicals (e.g. microcystins) and herbal remedies can also induce hepatotoxicity. Chemicals that cause liver injury are called hepatotoxins.

More than 900 drugs have been implicated in causing liver injury and it is the most common reason for a drug to be withdrawn from the market. Chemicals often cause subclinical injury to liver which manifests only as abnormal liver enzyme tests. Drug induced liver injury is responsible for 5% of all hospital admissions and 50% of all acute liver failures.

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