Medications

Dexamethasone enhances transgene expression

Dexamethasone, a glucocorticoid with anti-inflammatory and immunosuppressive effects, can transiently increase the expression of therapeutic genes delivered using adeno-associated virus (AAV) vectors. A new study, which showed ...

Medications

FDA approves Pfizer pill as first at-home COVID-19 treatment

(HealthDay)—The U.S. Food and Drug Administration on Wednesday approved the emergency use of the new Pfizer antiviral pill Paxlovid in people who are at high risk for severe COVID-19. It is the first approved treatment ...

Diseases, Conditions, Syndromes

Study on PFAs and fatty liver disease: Women more affected than men

Women are affected to a greater degree than men when exposed to PFAs, a group of highly fluorinated chemicals. A study from Örebro University shows how PFAs affect metabolism and lead to liver damage, so-called fatty liver ...

Medical research

'Good cholesterol' may protect liver

The body's so-called good cholesterol may be even better than we realize. New research from Washington University School of Medicine in St. Louis suggests that one type of high-density lipoprotein (HDL) has a previously unknown ...

Diseases, Conditions, Syndromes

Immune cells promote proinflammatory fatty liver disease

A particular type of dendritic cell is responsible for the tissue damage that occurs in non-alcoholic steatohepatits (NASH) in mice and humans. The dendritic cells cause aggressive, proinflammatory behavior in T cells, as ...

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