Oncology & Cancer

Gene discovery suggests new treatment approach for liver cancer

In a comprehensive analysis of human gene activation data, researchers from the Centenary Institute have discovered that the dipeptidyl peptidase-4 (DPP4) gene family is strongly implicated in the development of human hepatocellular ...

Oncology & Cancer

New treatment developed shows success in high-risk solid tumors

Despite intensive treatment, high-risk solid tumors like neuroblastoma, Ewing sarcoma, and rhabdomyosarcoma are challenging to cure because the disease in those high-risk patients does not respond to therapy. Conventional ...

Medical research

Even damaged livers can handle life-saving medication

When you ingest a drug—whether over-the-counter Tylenol or medication prescribed by a doctor—your liver is your body's first responder. And just like other first responders, sometimes the liver gets hurt. Doctors used ...

Genetics

CRISPR 'minigene' approach stops genetic liver disease in mice

A new CRISPR gene-editing technique prevented a genetic liver disease known to be driven by hundreds of different mutations and improved clinical symptoms in mice, Penn Medicine researchers reported in new proof-of-concept ...

Medications

FDA approves drug for most deadly form of tuberculosis

(HealthDay)—A new drug has been approved as part of a powerful, three-pronged treatment regimen for the most deadly strain of tuberculosis, the U.S. Food and Drug Administration announced Wednesday.

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