A prespecified interim analysis of the ongoing Phase 3 REGENERATE study has confirmed that obeticholic acid (OCA) is effective in the treatment of nonalcoholic steatohepatitis (NASH) with liver fibrosis. The 18-month analysis, ...
Apr 11, 2019
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Scientists have discovered a novel molecular pathway for an enzyme inhibitor in humans that plays a direct role in the development of high cholesterol and nonalcoholic fatty liver disease, which they then were able to reverse ...
Mar 25, 2019
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(HealthDay)—Two drugs have been approved by the U.S. Food and Drug Administration for the treatment of rare blood diseases, the agency announced Friday.
Dec 24, 2018
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An immunotherapy drug will be made available to some patients with advanced melanoma skin cancer on the NHS in England.
Nov 30, 2018
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Researchers at University of California San Diego School of Medicine have discovered using mice and human clinical specimens, that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis ...
Sep 13, 2018
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A team of researchers has uncovered a specific gene variant associated with an adverse drug reaction resulting in liver injury in a people with multiple sclerosis (MS). It is the first time researchers have been able to establish ...
Jul 16, 2018
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"Civilization begins with distillation," said William Faulkner, a writer and drinker. Although our thirst for alcohol dates back to the Stone Age, nobody has figured out a good way to deal with the ensuing hangover after ...
May 9, 2018
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A new study published today in the Journal of Pediatrics is the first to show that weight gain may have a negative impact on liver health in children as young as 8 years old. The study found that bigger waist circumference ...
Apr 4, 2018
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Researchers from Charité - Universitätsmedizin Berlin have identified an enzyme that has a major effect on glucose utilization in liver cells. The enzyme, retinol saturase, helps these cells adapt to variations in glucose ...
Sep 29, 2017
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(HealthDay)—In a report published online July 16 in the Journal of Clinical Pharmacy and Therapeutics, a case of survival after acute liver failure secondary to amiodarone administration is described.
Jul 19, 2017
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