Surgery

How a common drug causes liver failure

Acetaminophen is a common pain reliever found in every pharmacy. However, it is also the No. 1 cause of acute liver failure in the United States. In the liver, acetaminophen is converted into a new compound that covalently ...

Diseases, Conditions, Syndromes

p53 critical to recovering from acetaminophen overdose

Results from a new study show that after an acetaminophen overdose the p53 protein plays a key role in preventing the progression of liver damage and signaling the liver to repair itself. The findings could lead to new treatments ...

Medical research

Mechanisms in reversible infantile liver failure illuminated

Reversible infantile liver failure (RILF) is a heritable mitochondrial condition that causes severe liver dysfunction in infancy, but those who survive the acute stage typically recover and have no further problems. In work ...

Diseases, Conditions, Syndromes

Serious liver-related condition on the rise in the US

A new analysis reveals that cirrhosis and acute on chronic liver failure (ACLF, a deterioration of liver function in patients with cirrhosis that results in the failure of one or more organs) represent a substantial and increasing ...

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