Diseases, Conditions, Syndromes
Advanced alcohol-related liver disease on rise in US, study finds
The most deadly forms of alcohol-related liver disease appear to be on the rise in the U.S., a new study finds.
May 08, 2019
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News tagged with liver fibrosis
Genetics
Genome editing helps decipher a congenital liver disease
Congenital hepatic fibrosis (CHF) is a rare genetic disease that causes malformation and fibrosis (scarring) of the liver. Occurring in roughly one out of every 20,000 births, CHF can lead to an enlarged liver, impaired blood ...
May 08, 2019
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Diseases, Conditions, Syndromes
Novel biomarkers for noninvasive diagnosis of NAFLD-related fibrosis
With an estimated 25% of people worldwide affected by nonalcoholic fatty liver disease (NAFLD), there is a large unmet need for accurate, noninvasive measures to enhance early diagnosis and screening of hepatic fibrosis. ...
Apr 16, 2019
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Diseases, Conditions, Syndromes
Fibrosis, steatosis of the liver observed in some young adults
(HealthDay)—A considerable proportion of young adults have fibrosis and steatosis of the liver, according to a study presented at The International Liver Congress 2019, held from April 10 to 19 in Vienna.
Apr 12, 2019
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Diseases, Conditions, Syndromes
Aldo-keto reductase family 1 member B10 predicts advanced nonalcoholic steatohepatitis
AKR1B10 is a useful serum biomarker for advanced liver fibrosis in Nonalcoholic steatohepatitis, and combined with serum WFA(+)-M2BP, it can predict hepatocellular carcinoma development, gastroesophageal varix formation, ...
Apr 12, 2019
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Diseases, Conditions, Syndromes
Obeticholic acid improves liver fibrosis and other histological features of NASH
A prespecified interim analysis of the ongoing Phase 3 REGENERATE study has confirmed that obeticholic acid (OCA) is effective in the treatment of nonalcoholic steatohepatitis (NASH) with liver fibrosis. The 18-month analysis, ...
Apr 11, 2019
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Genetics
New study identifies genetic variant that could help reduce need for liver transplants
A new study from The Westmead Institute for Medical Research has identified a genetic variant associated with liver fibrosis (scarring) in chronic hepatitis C patients. This finding is a step toward reducing the number of ...
Apr 03, 2019
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Diseases, Conditions, Syndromes
Genetic relic of the 'black death' may offer clues in treating liver disease
A gene mutation that is believed to have safeguarded some people in 14th century Europe from the bubonic plague today may be protecting HIV patients co-infected with hepatitis C from potentially fatal liver scarring, says ...
Dec 03, 2018
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Diseases, Conditions, Syndromes
Researchers identify risk factors of advanced liver disease in cystic fibrosis patients
Children's Hospital Colorado (Children's Colorado) pediatric gastroenterologist, Michael Narkewicz, MD, recently shared results of the Prospective Study of Ultrasound to Predict Hepatic Cirrhosis in Cystic Fibrosis (PUSH), ...
Nov 12, 2018
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Diseases, Conditions, Syndromes
Interleukin IL-22, a new target to inhibit the progression of liver disease
Naglaa Shoukry, Ph. D., and her team have made a significant breakthrough in their research aiming to limit the progression of liver disease. They have characterized the mechanisms of action of type 3 inflammatory cytokines ...
Oct 27, 2018
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