Following the day-night cycle, the liver has its own metabolic rhythm. Using cutting-edge proteomics, scientists at EPFL and the Nestlé Institute of Health Sciences have now identified over 500 liver proteins that change ...
Nov 3, 2016
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While it has been more than 100 years since the discovery of insulin, metabolic diseases like diabetes, obesity and fatty liver continue to impact most of the population. More than one-third (36.5 percent) of adults in the ...
Jun 21, 2022
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Macrophages are cells of the immune system that, in addition to playing an essential role in the early response to microbial infection, also regulate tissue function and inflammation. Inflammation is a physiological response ...
Feb 3, 2023
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Although SGLT-2 inhibitors are central to the treatment of diabetes, their exact mode of action was hitherto unknown. In a study conducted by a research group led by Peter Wolf, Martin Krssak and Michael Krebs from MedUni ...
Feb 8, 2021
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A new study found that offspring born to mice that exercised during pregnancy were less likely to gain weight after consuming a high-fat diet later in life. Although previous studies have shown that exercise by obese females ...
Apr 7, 2019
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New research led by Western Sydney University suggests that aerobic exercise interventions incorporating either high-intensity interval training (HIIT) or moderate-intensity continuous training (MICT) are effective for improving ...
Dec 20, 2021
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Scientists from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) today reported that inhibiting a liver enzyme in obese mice decreased the rodents' appetite, increased energy expenditure ...
Apr 5, 2022
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An excess of bacteria in the gut can change the way the liver processes fat and could lead to the development of metabolic syndrome, according to health researchers.
Oct 29, 2015
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Nonalcoholic fatty liver disease (NAFLD) is one of the more common chronic liver diseases worldwide. It is associated with metabolic syndrome (i.e. insulin resistance and diabetes) and predisposes to cardiovascular disease. ...
Nov 13, 2017
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Mice given a new drug targeting a key gene involved in lipid and glucose metabolism could tolerate a high-fat diet regimen (composed of 60% fat from lard) without developing significant liver damage, becoming obese, or disrupting ...
Jan 21, 2020
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