(Medical Xpress)—An international team of researchers has discovered a way to silence the genes that cause transthyretin amyloidosis—a fatal genetic disease. In their paper published in the New England Journal of Medicine, ...
Living organisms have adapted to the day-night cycle and, in most cases, they have evolved a "circadian clock". Its effects are not completely known yet but its functioning has been shown to have important metabolic consequences ...
Jan 15, 2014
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A study, published in the journal Gene Expression and led by Brady Jin-Smith from the Department of Pathology at Tulane University, focuses on ALDHs, a group of key enzymes that catalyze the irreversible oxidation of various ...
Dec 15, 2023
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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes multi-organ damage, including liver dysfunction identified in more than 50% of COVID-19 patients. Liver damage in COVID-19 patients could be attributed to ...
Sep 21, 2022
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A new drug spurs liver regeneration after surgery, according to a paper published in The Journal of Experimental Medicine.
Aug 11, 2014
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The protein mTOR is a central controller of growth and metabolism. Deregulation of mTOR signaling increases the risk of developing metabolic diseases such as diabetes, obesity and cancer. In the current issue of the journal ...
Aug 11, 2014
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Obesity not only increases the risk of metabolic syndrome-related diseases, such as diabetes, fatty liver, and atherosclerosis, but also remarkably impacts seemingly unrelated conditions, such as cancer, psychiatric disorders, ...
Aug 24, 2023
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High levels of low-density lipoprotein (LDL) cholesterol increases the risk for coronary heart disease.
Jul 2, 2012
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New findings show how a genetically aberrant, fused protein promotes a rare form of liver cancer in adolescents and young adults. The researchers also saw that a certain mix of drugs could target the fused protein and the ...
Jul 9, 2019
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A new collaboration based at the University of Cambridge will aim to discover and develop new medicines to treat liver disease.
Sep 7, 2012
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