Massachusetts General Hospital (MGH) investigators have developed a novel strategy to protect the liver from drug-induced injury and improve associated drug safety. In their report receiving advance online publication in ...
Jan 15, 2012
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Researchers are working to improve drug testing to ensure newly developed drugs are safe for patients to take.
Oct 31, 2023
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A United States Food and Drug Administration mandate to limit the dosage of acetaminophen in pills that combine acetaminophen and opioid medications is significantly associated with subsequent reductions in serious liver ...
Mar 7, 2023
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State and federal public health agencies often understate the scientific evidence surrounding the toxicity of per- and polyfluoroalkyl substances (PFAS) in their public communications, according to an analysis published today ...
May 11, 2022
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Liver-on-a-chip devices capture the physiological and mechanical properties of the liver. They are commonly used by researchers to study how the liver metabolizes different compounds and drugs. In a new study seen in ACS ...
Jul 28, 2021
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When a new drug is being developed, the first question is, "Does it work?" The second question is, "Does it do harm?" No matter how effective a therapy is, if it harms the patient in the process, it has little value.
Apr 8, 2021
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Hesperos Inc., pioneers of the "human-on-a-chip" in vitro system has announced the use of its innovative multi-organ model to successfully measure the concentration and metabolism of two known cardiotoxic small molecules ...
Jul 3, 2019
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One in four people in Western and Asian societies develop a build-up of fat in the liver as a result of an unhealthy diet. This disease – referred to as non-alcoholic fatty liver disease (NAFLD) – causes no symptoms initially ...
Mar 1, 2019
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Scientists at Wake Forest Institute for Regenerative Medicine (WFIRM) have developed the most sophisticated mini-livers to date. These organoids can potentially help scientists better understand certain congenital liver diseases ...
Feb 13, 2018
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Compared to controls, patients with psoriasis (PsO) are at higher risk for serious liver disease than patients with rheumatoid arthritis - two autoimmune diseases often treated with similar drugs that can cause liver damage, ...
Nov 2, 2017
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